de la hipertensión y la inhibición de los mecanismos de contrarregulación, así como en una reducción de los efectos adversos. calcioantagonistas. eficacia. Adicionalmente, el artículo se referirá a los potenciales efectos adversos del . lo mismo puede establecerse para los calcio antagonistas no dihidropiridínicos. También son muy bien tolerados con muy pocos efectos adversos, en su mayoría nadolol), antidepresivostricíclicos (amitriptilina)21, calcioantagonistas.

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Effect ofcolesevelam on lovastatin pharmacokinetics. The effect of fluvastatin on the pharmacokinetics and pharmacodynamics of ezetimibe. Effects of rosuvastatin on platelet inhibition by clopidogrel in cardiovascular patients. The effect of the newly developed angiotensin receptor II antagonist fimasartan on the pharmacokinetics of atorvastatin in relation to Efecto in healthy male volunteers. Finally, a method was used to assess the clinical relevance of the interaction, based on the likelihood of occurrence and the severity of the effect of the interaction.

Similarmente, este efecto se presenta con la colestiramina y la glipizida Pharmacokinetic interactions of the oral renin inhibitor aliskiren with lovastatin, atenolol, celecoxib and cimetidine.

Potential interaction between troglitazone and atorvastatin. Effect of clopidogrel on the steady-state pharmacokinetics of fluvastatin. Negredo E, Rey-Joly yC.

Lack of adverse clopidogrel-atorvastatin clinical interaction from secondary analysis of a randomized, placebo-controlled clopidogrel trial. J Cardiovasc Pharmacol Ther. Amiodarone interacts with simvastatin but not with pravastatin disposition kinetics. Duration of effect of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin. Simvastatin-diltiazem drug interaction resulting in rhabdomyolysis and hepatitis.


Can J Clin Pharmacol. Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: Thirty-three of them were considered of very high risk level 1 and 42 of high risk level 2basically associated to increased risk for rhabdomyolisis. Steady state serum concentrations of pravastatin and digoxin when given in combination. Simvastatin coprescribed with protease inhibitors despite dangerous drug interactions.

Possible colchicine rhabdomyolysis in a fluvastatin-treated patient. Effect of gemfibrozil on the pharmacokinetics of pioglitazone. J Pharmacol Exp Ther. Simvastatin-associated rhabdomyolysis after coadministration of macrolide antibiotics in two patients.

Henao 1M. Hypolipidemic agents drug interactions: Rhabdomyolysis with concurrent atorvastatina and diltiazem.

Rhabdomyolysis associated with concurrent use of simvastatina and diltiazem. De igual manera, la ciclosporina aumenta en 3,4 veces el ABC de ezetimiba Harvengt C, Desager JP.

John’s wort product Movina and atorvastatin in patients with hypercholesterolemia.

Calcio Antagonistas by David Dominguez Guzman on Prezi

Lack of effect of bezafibrate and fenofibrate on the pharmacokinetics and pharmacodynamics of repaglinide. Lack of pharmacokinetic interaction of colestipol and fenofibrate in volunteers.

The effect of gemfibrozil on repaglinide pharmacokinetics persists for at least 12 h after the dose: Am J Med Sci. Cardiovascular risk and human immunodeficiency virus infection: Enzymatic inhibition of CYP was the most common mechanism for these interactions. J Am Board Fam Med. Presumed interaction of fusidic acid with simvastatin.


J Acquir Immune Defic Syndr. Pharmacokinetic interactions between protease inhibitors and statins in HIV seronegative volunteers: Br J Hosp Med Lond. Pharmacokinetic interactions between alitretinoin and ketoconazole or simvastatin or ciclosporin A. Potential interaction between warfarin and fluvastatin.

Thompson M, Samuels S. Rhabdomyolysis induced by simvastatin-fluconazole combination. Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: Inhibition of the organic anion-transporting polypeptide 1B1 by quercetin: A new clinical challenge.

Acute myopathy in a patient with concomitant use of pravastatin and colchicine.

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Evaluation of the potential for pharmacokinetic interaction between fenofibrate and ezetimibe: Effects of a concomitant single oral dose of rifampicin on the pharmacokinetics of pravastatina in a two-phase, randomized, single-blind, placebo-controlled, crossover study in healthy Chinese male subjects. Plasma concentrations of active lovastatin acid are markedly increased by gemfibrozilo but not by bezafibrate.

Atorvastatin does not produce a clinicallysignificant effect on the pharmacokinetics of terfenadine.